作者: Charles V. Jackson , John H. McNeill
DOI: 10.1007/978-1-4612-5172-9_5
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摘要: The term smooth muscle relaxant encompasses a broad spectrum of agents that relax both vascular and non muscle. Therapeutically these relaxants are used for the treatment bronchospastic disorders, premature labor, variety cardiovascular disorders (e.g., hypertension, angina pectoris, peripheral disease, arrhythmias, congestive heart failure). A few have proven to be useful tools investigational purposes, example, xanthines (phosphodiesterase inhibition role cyclic 3′,5′-monophosphate in mediating cellular events) calcium-channel blockers (elucidating calcium normal cell function drug action). This chapter attempts discuss current pharmacodynamics, pharmacokinetics, clinical pharmacology give researcher, clinician, graduate medical student basic information on compounds.