Meniscus Regeneration in a Rabbit Partial Meniscectomy Model

摘要: Meniscectomy is known to be associated with osteoarthrosis of the knee. The purpose this study was compare natural and augmented repair menisci in knees New Zealand White rabbits. To create a partial defect medial meniscus, we used an experimental model that has been well characterized extensively articular cartilage repair. left untreated or treated one following: periosteal autograft, type I collagen sponge, same sponge loaded autologous, bone marrow-derived, cultured mesenchymal stem cells. always incomplete degenerative changes within these joints were progressive. autograft underwent differentiation into hyaline composite ineffectual as meniscus accelerated those when compared controls. There evidence consistent sequence events transformatio...