Clastogenic effects of copper sulphate on the bone marrow chromosomes of mice in vivo.
作者： Kalpana Agarwal , Archana Sharma , Geeta Talukder
DOI: 10.1016/0165-7992(90)90115-Z
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摘要: Copper sulphate administered intraperitoneally to Swiss albino mice in vivo induced a significant increase the frequency of chromosomal aberrations bone marrow cells as all concentrations used (1.1-6.6 mg/kg b.w.), when compared negative control. Statistical analysis indicates that degree clastogenicity was directly related and indirectly period exposure. The effect maximal at 6 h after treatment with 12 24 h.
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