Biodegradable polymers for delivery of therapeutic agents

作者: Melissa D. Krebs

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摘要: Methods, processes, systems, and compositions for treating disease are disclosed. In some cases, the present disclosure provides delivery of therapeutic agents, in an active form, to a localized area, over extended period time. one embodiment, disclosed composition may comprise agent biodegradable polymer and/or microsphere.

参考文章(17)
Nikos Panayotatos, Jeffrey Fasick, Kwong Y. Tsang, Humanized monoclonal antibody 31.1 as an anticancer agent ,(2005)
Dawn Winsor-Hines, Patricia Rao, Douglas J. Ringler, Inducing tolerance in primates ,(2003)
Randall J Lee, Mark Maciejewski, Francis Rauh, Method and systems for using biopolymer-based beads and hydrogels ,(2007)
Weiliam Chen, Lihui Weng, Load bearing hydrogel implants ,(2009)
Yoon Ki Joung, Jong Hoon Choi, Kyung Min Park, Ki Dong Park, PLGA microparticle-embedded thermosensitive hydrogels for sustained release of hydrophobic drugs. Biomedical Materials. ,vol. 2, pp. 269- 273 ,(2007) , 10.1088/1748-6041/2/4/010
Rebecca R. Torelli-Souza, Layanna A. Cavalcante Bastos, Hermano G. L. Nunes, Celso A. Camara, Rosa Valéria S. Amorim, Sustained release of an antitumoral drug from alginate‐chitosan hydrogel beads and its potential use as colonic drug delivery Journal of Applied Polymer Science. ,vol. 126, ,(2012) , 10.1002/APP.36928
Philipp Holliger, Peter J Hudson, Engineered antibody fragments and the rise of single domains Nature Biotechnology. ,vol. 23, pp. 1126- 1136 ,(2005) , 10.1038/NBT1142
Paul J. Carter, Potent antibody therapeutics by design Nature Reviews Immunology. ,vol. 6, pp. 343- 357 ,(2006) , 10.1038/NRI1837
Jie Ma, John Samuel, Glen S. Kwon, Antoine A. Noujaim, Ragupathy Madiyalakan, Induction of anti-idiotypic humoral and cellular immune responses by a murine monoclonal antibody recognizing the ovarian carcinoma antigen CA125 encapsulated in biodegradable microspheres Cancer Immunology, Immunotherapy. ,vol. 47, pp. 13- 20 ,(1998) , 10.1007/S002620050499