Assessing TP53 status in human tumors: Lessons from breast cancer
作者： Anita Langerød , Magali Olivier , Anne-Lise Børresen-Dale
DOI: 10.1007/978-1-4614-3676-8_9
关键词:
摘要: Somatic mutations in the TP53 gene are frequently found many types of cancer. Various methods have been developed order to meet challenges assessing mutation status human tumors and most commonly used techniques will be presented show advancement current trends. is further discussed context whole genome analysis, which may elucidate network, uncover profiles substitute previous detection methods, more applicable different aspects clinical decision making. As breast cancer one diseases where shows significant prognostic impact potential, chapter based on experiences from research this tumor type.
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