Acoustic and mechanical characterization of 3D-printed scaffolds for tissue engineering applications
作者： Mitra Aliabouzar , Grace Lijie Zhang , Kausik Sarkar
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摘要: The acoustic and mechanical properties of 3D-printed porous poly-(ethylene glycol)-diacrylate (PEGDA) hydrogel scaffolds were investigated using an ultrasound pulse echo technique on different scaffold microstructures (solid, hexagonal square pores). Acoustic parameters such as speed sound, impedance attenuation coefficient well physical the pore structure, effective density elastic moduli determined. results show that microstructure (porosity geometry) plays a crucial role in defining scaffolds, achieving highest for with pores showing decrease sound increasing porosity. also found to be similar those soft tissues, making PEGDA suitable candidate tissue engineering applications. To evaluate their cellular performance, adhesion proliferation human mesenchymal stem cells (hMSCs) these investigated. performed better than solid one, recording cell attachment growth pores.
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