Prostate Cancer Stem Cells: A Brief Review
作者： Xin Chen , Dean G. Tang
DOI: 10.1007/978-1-4614-6498-3_3
关键词:
摘要: Human cancers have been shown to harbor stem cell-like cells called cancer (CSCs). These are thought be endowed with indefinite self-renewal ability and believed involved in tumor initiation, promotion, progression, metastasis, therapy resistance. Prostate (PCa) also contain CSCs. Here we briefly review the literature reports of CSCs various systems. We then summarize studies prostate (PCSCs) human mouse models discuss their respective limitations. further current controversies respect identifying cell origin for PCa. Elucidating unique characteristics PCSCs will enhance our understanding mechanisms underlying emergence castration-resistant disease may provide new opportunities developing therapeutics that target recurrent
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