Vitamin D deficiency and type 2 diabetes.

作者: Z. Ozfirat , T. A. Chowdhury

DOI: 10.1136/PGMJ.2009.078626

关键词:

摘要: Type 2 diabetes is a major public health problem, accounting for significant premature mortality and morbidity. The growth in prevalence of the condition appears to be closely linked with obesity. Over last 5 years, number large observational studies have suggested an association between onset type Vitamin D deficiency. has important effects on insulin action, may impact pathways which importance development diabetes. This article reviews evidence linking deficiency pathogenesis diabetes, suggests areas urgent further research determine whether replacement role prevention

参考文章(85)
Gisela Wilcox, Insulin and Insulin Resistance The Clinical biochemist. Reviews / Australian Association of Clinical Biochemists. ,vol. 26, pp. 19- 39 ,(2005)
T Tankova, G Kirilov, R Kovacheva, L Dakovska, A M Borissova, The effect of vitamin D3 on insulin secretion and peripheral insulin sensitivity in type 2 diabetic patients. International Journal of Clinical Practice. ,vol. 57, pp. 258- 261 ,(2003)
Dana A. Procsal, Helen L. Henry, Ernest J. Friedlander, Anthony W. Norman, Studies on the mode of action of calciferol. Biological activity of 1 alpha, 24R,25-trihydroxyvitamin D3 in the chick. Archives of Biochemistry and Biophysics. ,vol. 179, pp. 229- 234 ,(1977) , 10.1016/0003-9861(77)90107-2
Heather B Del Valle, A Catharine Ross, Ann L Yaktine, Christine L Taylor, Dietary Reference Intakes for Calcium and Vitamin D ,(2013)
Ken C Chiu, Audrey Chu, Vay Liang W Go, Mohammed F Saad, None, Hypovitaminosis D is associated with insulin resistance and β cell dysfunction The American Journal of Clinical Nutrition. ,vol. 79, pp. 820- 825 ,(2004) , 10.1093/AJCN/79.5.820
Margherita T Cantorna, Yan Zhu, Monica Froicu, Anja Wittke, Vitamin D status, 1,25-dihydroxyvitamin D3, and the immune system The American Journal of Clinical Nutrition. ,vol. 80, ,(2004) , 10.1093/AJCN/80.6.1717S
J. A. Johnson, J. P. Grande, P. C. Roche, R. Kumar, Immunohistochemical localization of the 1,25(OH)2D3 receptor and calbindin D28k in human and rat pancreas American Journal of Physiology-endocrinology and Metabolism. ,vol. 267, ,(1994) , 10.1152/AJPENDO.1994.267.3.E356
J. R. Ortlepp, J. Metrikat, M. Albrecht, A. von Korff, P. Hanrath, R. Hoffmann, The vitamin D receptor gene variant and physical activity predicts fasting glucose levels in healthy young men. Diabetic Medicine. ,vol. 20, pp. 451- 454 ,(2003) , 10.1046/J.1464-5491.2003.00971.X
Michael B. Zemel, Warren Thompson, Anita Milstead, Kristin Morris, Peter Campbell, Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults. Obesity Research. ,vol. 12, pp. 582- 590 ,(2004) , 10.1038/OBY.2004.67
M. Fasshauer, R. Paschke, Regulation of adipocytokines and insulin resistance. Diabetologia. ,vol. 46, pp. 1594- 1603 ,(2003) , 10.1007/S00125-003-1228-Z