Lactobacillus reuteri KT260178 Supplementation Reduced Morbidity of Piglets Through Its Targeted Colonization, Improvement of Cecal Microbiota Profile, and Immune Functions

摘要: Supplementing suckling piglets with Lactobacillus reuteri isolated from a homologous source improves L. colonization number in the gastrointestinal tract, which can have health benefits. This study investigated dietary supplementation on growth and health—including immune status—of piglets, as well its colonization. A total of 60 sows similar parity body weight were allocated into one three groups after secretion (n = 20 each, 10 neonatal each): untreated control, supplementation, antibiotic treatment. The experimental duration was 28 days, birth to their group transferred. For first 7 days birth, all fed by sows. Piglets administered 1.0 ml L. fermentation broth containing 5.0 × 107 CFU. From 7 given basal feed (control), supplemented (1.0 × 107 CFU/g), or aureomycin (150 mg/kg). distal jejunum ileum increased reuteri-supplemented compared control determined fluorescence situ hybridization real-time PCR analysis. Total Bifidobacterium counts cecum higher whereas aerobic bacteria (Escherichia coli Staphylococcus) lower group. also improved antioxidant status function relative animals. Strain-specific colonizes intestinal mucosa cecal microbiota profile whole-body status, leading better morbidity mortality rates.