Early post-transplant medical compliance and mental health predict physical morbidity and mortality one to three years after heart transplantation

作者: Mary Amanda Dew , Robert L Kormos , Loren H Roth , Srinivas Murali , Andrea DiMartini

DOI: 10.1016/S1053-2498(98)00044-8

关键词:

摘要: Abstract Background Poor medical compliance has been held responsible for a large proportion of deaths occurring subsequent to initial postoperative recovery. However, beyond clinical reports, there little empirical examination this issue, or the extent which major psychiatric disorder and failure adjust transplant predict long-term physical morbidity mortality. We prospectively examined whether full range behaviors outcomes during first year post-transplant predicted mortality through 3 years post-transplant. Methods A total 145 heart recipients who had received detailed mental health assessments were followed up at Interview data corroborative information from family members used determine in multiple domains, diagnoses, symptomatology post-surgery. Medical record reviews performed abstract on acute graft rejection episodes, incident cardiac allograft disease (CAD) 1 Results After controlling known transplant-related predictors outcome, multivariate analyses yielded following significant ( p Conclusions The findings, plus we have previously reported that showed patients are most likely problems early post-transplant, suggest interventions focused maximizing patients' psychosocial status these areas may further improve population.

参考文章(89)
R C Bourge, J Jarcho, D G Pitts, T W Shroyer, J K Kirklin, D C Naftel, R C Starling, M L Barr, Influence of HLA mismatch on rejection after heart transplantation: A multiinstitutional study Journal of Heart and Lung Transplantation. ,vol. 13, pp. 583- 596 ,(1994)
Cooper Dk, Tripp J, Paris W, Zuhdi N, Sisson S, Medication noncompliance and its relationship to financial factors after heart transplantation. Journal of Heart and Lung Transplantation. ,vol. 13, pp. 930- ,(1994)
R. L. Kormos, M. A. Dew, L. H. Roth, B. P. Griffith, M. E. Thompson, Medical compliance and its predictors in the first year after heart transplantation. Journal of Heart and Lung Transplantation. ,vol. 15, pp. 631- 645 ,(1996)
K. Ramireddy, H. O. Ventura, M. R. Mehra, D. D. Stapleton, F. W. Smart, R. B. Chambers, The prognostic impact of immunosuppression and cellular rejection on cardiac allograft vasculopathy: Time for a reappraisal Journal of Heart and Lung Transplantation. ,vol. 16, pp. 743- 751 ,(1997)
Psychiatric aspects of organ transplantation. American Journal of Psychiatry. ,vol. 146, pp. 972- 982 ,(1989) , 10.1176/AJP.146.8.972
Julian A. Smith, The Stanford manual of cardiopulmonary transplantation Futura Pub. Co.. ,(1996)
John B. O'Connell, Michael P. Kaye, Heart and lung transplantation 2000 R.G. Landes, c1993. ,(1993)
H. A. Valantine, J. S. Schroeder, Transplant Coronary Disease Heart Failure Mechanisms and Management. pp. 466- 474 ,(1991) , 10.1007/978-3-642-58231-8_50
David L. Sackett, R. Brian Haynes, D. Wayne Taylor, Compliance in health care Johns Hopkins University Press. ,(1979)