Is the aggressive management of hyperlipidemia in nephrotic syndrome mandatory

摘要: The development of the nephrotic syndrome is associated with a lipid profile characterized by increased total and low density lipoprotein cholesterol. Although high (HDL) values may be in normal range, there frequently abnormalities HDL subclasses, reduction mature HDL2 subfraction. While these changes considered risk for atherosclerosis, they revert to remission syndrome. However, chronic range proteinuria, persist also levels (a), very light further reductions HDL. These factors could all contribute greater atherosclerosis. coronary artery disease seen patients end-stage renal disease, many uncontrolled studies have suggested an prevalence cardiovascular no prospective evaluate relationship between cardiac been performed Recent experimental data hyperlipidemia progressive injury. Unfortunately, human epidemiological are incomplete correlating No therapeutic trials tested whether or not pharmacologic interventions will benefit either that ensues persistent Thus, considerably more needed help clarify this important area.