STR-based genetic structure of the Berber population of Bejaia (Northern Algeria) and its relationships to various ethnic groups.

摘要: Patterns of genetic variation in human populations have been described for decades. However, North Africa has received little attention and Algeria, particular, is poorly studied, Here we genotyped a Berber-speaking population from Algeria using 15 short tandem repeat (STR) loci D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 FGA the commercially available AmpF/STR Identifiler kit. Altogether 150 unrelated Algerian individuals were sampled across 10 administrative regions or towns Bejaia Wilaya (administrative district). We found that all STR met Hardy-Weinberg equilibrium expectations, after Bonferroni correction presented high level observed heterozygosity system (>0.7). Genetic parameters forensic interest such as combined power discrimination (PD) probability exclusion (PE) showed values higher than 0.999, suggesting this set STRs can be used studies. Our results also compared to those published 42 other analyzed with same set. sample clustered several African but some geographically close populations, including Mozabite closer Near-Eastern populations. While able detect structure among samples, it was not correlated language (Berber-speaking versus Arab-speaking) geography (east west). In words, no significant differences between Arab-speaking Africa. The closeness European, suggest should integrated models aiming at reconstructing demographic history Europe. Similarly, proximity sub-Saharan reminder links connect regions.