What Is Normal

作者: N. J. Smith

DOI: 10.1080/1086508X.2000.11079306

关键词:

摘要: ABSTRACT.For most quantities measured in clinical medicine, healthy subjects produce a range of values which overlaps the found patients with disease, so that there is no sharp distinction between normal and abnormal. Furthermore, word “normal” ambiguous potentially misleading. The “normal range” has therefore been superseded laboratory work by 95% reference interval, includes from population. probability person producing value outside interval 0.05, or one twenty. Determining reliable requires representative sample at least 120, preferably 200, population, many more may be needed if distribution asymmetrical. Subjects should chosen according to clearly defined criteria. possibility correlation age, height, etc. considered, calculated method appropriate data...

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