Acceptability of daily pre-exposure prophylaxis among adolescent men who have sex with men, travestis and transgender women in Brazil: A qualitative study.

摘要: Background Adolescents face socio-structural, personal and programmatic barriers to HIV prevention services, highlighting the importance of understanding knowledge acceptability as essential aspects promote their broader access pre-exposure prophylaxis (PrEP). We analyzed PrEP among adolescent men who have sex with (MSM), travestis transgender women (TGW). Methods A qualitative investigation was conducted part formative research PrEP15-19 study, an ongoing demonstration study that analyzes effectiveness daily MSM, TGW aged 15-19 in three Brazilian cities. total 37 semi-structured interviews 6 focus groups were conducted. Building from thematic analysis focusing on participants' sexual encounters, perceptions about efficacy, vulnerability contexts, we prospective PrEP. Findings Knowledge incipient characterized by adolescents' frequent doubts its prescription efficacy. The 'ideal' use appeared together consistent condom use, especially casual sex. also mentioned depending increased learning management over time. Main included incorporation a medication into routine impact social lives, related stigma. Concerns short- long-term side effects reported use. contrasted using precarity life conditions, some expressed critical vision associating it pharmaceuticalization trans necropolitics. Conclusions Participants' low are circumscribed rigid perception ideal method context relations. Prospective highlights successful uptake depends overcoming health services confronting transphobia homophobia care.