A systematic approach for the diagnosis and treatment of idiopathic peptic ulcers.

摘要: An idiopathic peptic ulcer is defined as an with unknown cause or that appears to arise spontaneously. The first step in treatment exclude common possible causes, including Helicobacter pylori infection, infection other pathogens, ulcerogenic drugs, and uncommon diseases upper gastrointestinal manifestations. When all known causes are excluded, a diagnosis of can be made. A patient whose may have higher risk for complicated disease, poorer response gastric acid suppressants, recurrence rate after treatment. Risk factors associated this disease include genetic predisposition, older age, chronic mesenteric ischemia, smoking, concomitant diseases, American Society Anesthesiologists score, stress. Therefore, the management emerging should systematically explore treat underlying while regular endoscopic surveillance confirm healing use proton-pump inhibitors on case-by-case basis.