Secondary, AA, Amyloidosis

作者: Riccardo Papa , Helen J. Lachmann

DOI: 10.1016/J.RDC.2018.06.004

关键词:

摘要: AA amyloidosis, otherwise known as secondary is a complication of chronic inflammation. The amyloid fibrils are derived from the hepatic acute phase reactant, serum A protein. Clinically amyloidosis has predominantly renal presentation with proteinuria and impairment. Untreated disease will progress to end-stage failure. Treatment depends on complete control underlying inflammatory condition, if this can be achieved long-term outcomes favourable. Median survival in patients now exceeds 12 years although failure eventually develops more than 40%.

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