Immunologic aspects of human sarcomas.

摘要: Considerable evidence has been accumulated from clinical and laboratory observations to support the concept that host factors influence development progression of human sarcomas. There is suggestive immunologic response patient his sarcoma one such factor. Thus, EVERSON COLE (8), other authors have cited specific case reports spontaneous regression tumors, including various Conversely, WOODRUFF sudden appearance sarcomas after long latent periods, sometimes coinciding with immunosuppressive therapy (36). Other (11, 21) noted failure circulating tumor cells in autotransplants metastasize. Others an increased incidence malignant disease patients congenital deficiency diseases (9) those receiving treatment for renal homografts (14, 23). WILSON et al. disseminated neoplasms cessation drugs organ transplant who inadvertently received allografts cancer (33). The results a study survived longer than 10 years osteogenic suggested survivors had better immune responses did nonsurvivors (22).