The effects of plasticizers on the ovary.

摘要: Endocrine disrupting chemicals pose a threat to health and reproduction. Plasticizers such as phthalates bisphenols are particularly problematic because they present in many consumer products exposure can begin utero continue throughout the lifetime of individual. Evidence suggests that these have ancestral transgenerational effects, making them huge public concern for reproductive current future generations. Studies performed rodents or using rodent- human-derived tissues been critical understanding toxic effects plasticizers on ovary their mechanisms action. This review addresses vitro rodent-based vivo studies investigating ovarian health, female reproduction, correlations between human pathologies.