摘要: Arteriosclerotic narrowing of cerebral arteries was once viewed as the key to mental decline. As Alzheimer9s disease gained recognition and concept multi-infarct dementia achieved acceptance, vascular came be regarded uncommon. The changing nature disease, aging population widespread use brain imaging techniques have brought new prominence dementia, chiefly in form an epidemic "Binswanger9s disease". Growing evidence suggests that not only grey matter lesions but also white contribute factors commonly coexist interact with Alzheimer changes has a potentially treatable component. Vascular needs redefined, reappraised reinvestigated.