Behavioral performance effects of nicotine in smokers and nonsmokers.

摘要: Abstract Performance on finger-tapping and handsteadiness, tasks opposite in response requirements, was compared between male smokers nonsmokers (n = 10 each) two occasions, once following intake of nicotine (15 μg/kg) by measured-dose nasal spray placebo. Compared with nonsmokers, had significantly greater increase speed due to nicotine. On the other hand, tended have improved performance handsteadiness (i.e., less involuntary movement) nicotine, while impaired performance, although this difference not significant. Nicotine-induced changes each task were inversely related, suggesting specificity behavioral effects depending demands, rather than a generalized effect. These may be important understanding reinforcing value intake, differences as function smoking history suggest chronic adaptation