Dental epithelial stem cells

摘要: The only dental epithelial cells present in adult human teeth are the cell rests of Malassez covering roots as a thin network. They have been suggested to exhibit stem properties, but there is no evidence their capacity generate epithelium. So far, continuously growing mouse incisor has provided best model for research on cells. These reside niche located cervical loop, and regulation maintenance, proliferation, differentiation actively studied. All originate from embryonic primary lamina replacement develop its extension, successional lamina. Apparently, progenitors all lineages lamina, associated with tooth morphogenesis. Further characterization progenitor determination whole and/or enamel goals worth pursuing future research.