Melanoma: epidemiology, risk factors, pathogenesis, diagnosis and classification.

作者: Mauro Salvatore Alessandro Alaibac , Saveria Tropea , Carlo Riccardo Rossi , Marco Rastrelli

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摘要: This article reviews epidemiology, risk factors, pathogenesis and diagnosis of melanoma. Data on melanoma from the majority countries show a rapid increase incidence this cancer, with slowing rate in period 1990-2000. Males are approximately 1.5-times more likely to develop than females, while according other studies, different prevalence both sexes must be analyzed relation age: is grater women men until they reach age 40 years, however, by 75 years age, almost 3-times as high versus women. The most important potentially modifiable environmental factor for developing malignant exposure ultraviolet (UV) rays because their genotoxic effect. Artificial UV may play role development host factors number melanocytic nevi, familiar history genetic susceptibility. A patient personal considered at greater subsequent Indeed 1-8% patients prior will multiple primary melanomas. We herein review dermatological classification

参考文章(39)
Caroline Bevona, William Goggins, Timothy Quinn, Julie Fullerton, Hensin Tsao, Cutaneous melanomas associated with nevi. Archives of Dermatology. ,vol. 139, pp. 1620- 1624 ,(2003) , 10.1001/ARCHDERM.139.12.1620
Allan C. Halpern, Dysplastic Nevi as Risk Markers of Sporadic (Nonfamilial) Melanoma Archives of Dermatology. ,vol. 127, pp. 995- 999 ,(1991) , 10.1001/ARCHDERM.1991.01680060069006
Lyn McDivitt Duncan, The Classification of Cutaneous Melanoma Hematology-oncology Clinics of North America. ,vol. 23, pp. 501- 513 ,(2009) , 10.1016/J.HOC.2009.03.013
Margaret A. Tucker, Clinically Recognized Dysplastic Nevi JAMA. ,vol. 277, pp. 1439- 1444 ,(1997) , 10.1001/JAMA.1997.03540420035026
Giuseppe Argenziano, H.Peter Soyer, Sergio Chimenti, Renato Talamini, Rosamaria Corona, Francesco Sera, Michael Binder, Lorenzo Cerroni, Gaetano De Rosa, Gerardo Ferrara, Rainer Hofmann-Wellenhof, Michael Landthaler, Scott W. Menzies, Hubert Pehamberger, Domenico Piccolo, Harold S. Rabinovitz, Roman Schiffner, Stefania Staibano, Wilhelm Stolz, Igor Bartenjev, Andreas Blum, Ralph Braun, Horacio Cabo, Paolo Carli, Vincenzo De Giorgi, Matthew G. Fleming, James M. Grichnik, Caron M. Grin, Allan C. Halpern, Robert Johr, Brian Katz, Robert O. Kenet, Harald Kittler, Jrgen Kreusch, Josep Malvehy, Giampiero Mazzocchetti, Margaret Oliviero, Fezal zdemir, Ketty Peris, Roberto Perotti, Ana Perusquia, Maria Antonietta Pizzichetta, Susana Puig, Babar Rao, Pietro Rubegni, Toshiaki Saida, Massimiliano Scalvenzi, Stefania Seidenari, Ignazio Stanganelli, Masaru Tanaka, Karin Westerhoff, Ingrid H. Wolf, Otto Braun-Falco, Helmut Kerl, Takeji Nishikawa, Klaus Wolff, Alfred W. Kopf, Dermoscopy of pigmented skin lesions: results of a consensus meeting via the Internet Journal of The American Academy of Dermatology. ,vol. 48, pp. 679- 693 ,(2003) , 10.1067/MJD.2003.281
Elizabeth A. Holly, John W. Kelly, Steven N. Shpall, Shu-Hui Chiu, Number of melanocytic nevi as a major risk factor for malignant melanoma Journal of the American Academy of Dermatology. ,vol. 17, pp. 459- 468 ,(1987) , 10.1016/S0190-9622(87)70230-8
Hensin Tsao, Kristin Niendorf, Genetic testing in hereditary melanoma Journal of The American Academy of Dermatology. ,vol. 51, pp. 803- 808 ,(2004) , 10.1016/J.JAAD.2004.04.045
Linda Titus-Ernstoff, Ann E. Perry, Steven K. Spencer, Jennifer J. Gibson, Bernard F. Cole, Marc S. Ernstoff, Pigmentary characteristics and moles in relation to melanoma risk International Journal of Cancer. ,vol. 116, pp. 144- 149 ,(2005) , 10.1002/IJC.21001
Andrew J. Watt, Sandra V. Kotsis, Kevin C. Chung, Risk of melanoma arising in large congenital melanocytic nevi: A systematic review Plastic and Reconstructive Surgery. ,vol. 113, pp. 1968- 1974 ,(2004) , 10.1097/01.PRS.0000122209.10277.2A