Hydrogen peroxide-inducible proteins in Salmonella typhimurium overlap with heat shock and other stress proteins.

摘要: Abstract Hydrogen peroxide treatment induces the synthesis of 30 proteins in Salmonella typhimurium. Five these are also induced by heat shock, including highly conserved DnaK protein. The induction one five shock is dependent on oxyR, a positive regulator hydrogen peroxide-inducible genes, while other four oxyR independent. have been identified, and their structural genes mapped. Other stresses such as nalidixic acid, ethanol, or cumene hydroperoxide induce subsets well additional proteins. Hydrogen shown to be largely different from those aerobiosis. In addition, expression katG (catalase) gene regulated at level mRNA.