Differential Expression of HER-2/NEU Receptor of Invasive Mammary Carcinoma Between Caucasian and African American patients in the Detroit Metropolitan Area. Correlation with Overall Survival and Other Prognostic Factors

作者: M. A. Al-Abbadi , T. A. Washington , H. A. Saleh , S. E. Tekyi-Mensah , D. R. Lucas

DOI: 10.1007/S10549-005-5149-Z

关键词:

摘要: Goals. HER-2/neu overexpression in invasive mammary carcinoma is associated with more aggressive biologic behavior. Breast cancer African American (AA) women has been a shorter survival rate than that seen Caucasians (C). This study evaluated the frequency of HER-2/neu C compared to AA patients and association expression overall other prognostic factors.

参考文章(33)
Sandra C. Garmon Bibb, The relationship between access and stage at diagnosis of breast cancer in African American and Caucasian women. Oncology Nursing Forum. ,vol. 28, pp. 711- 719 ,(2001)
Royak-Schaler R, Rose Dp, Tumor biology and prognosis in black breast cancer patients: a review. Cancer Detection and Prevention. ,vol. 25, pp. 16- 31 ,(2001)
H. Bhat, J. V. Vadgama, Yanyuan Wu, R. Chillar, Dejun Shen, M. Subbarao, Mutation analysis of BRCA1 gene in African-American patients with breast cancer. Journal of The National Medical Association. ,vol. 92, pp. 29- 35 ,(2000)
M F Press, L Bernstein, P A Thomas, L F Meisner, J Y Zhou, Y Ma, G Hung, R A Robinson, C Harris, A El-Naggar, D J Slamon, R N Phillips, J S Ross, S R Wolman, K J Flom, HER-2/neu gene amplification characterized by fluorescence in situ hybridization: poor prognosis in node-negative breast carcinomas. Journal of Clinical Oncology. ,vol. 15, pp. 2894- 2904 ,(1997) , 10.1200/JCO.1997.15.8.2894
Olufunmilayo I. Opolade, Qing Gao, Clement A. Adebamowo, James Fackenthal, Soma Das, Lise Sveen, Adeyinka G. Falusi, Protein truncating BRCA1 and BRCA2 mutations in African women with pre-menopausal breast cancer. Human Genetics. ,vol. 107, pp. 192- 194 ,(2000) , 10.1007/S004390000342
Patricia G. Moorman, Beth A. Jones, Robert C. Millikan, Ingrid J. Hall, Beth Newman, Race, Anthropometric Factors, and Stage at Diagnosis of Breast Cancer American Journal of Epidemiology. ,vol. 153, pp. 284- 291 ,(2001) , 10.1093/AJE/153.3.284
A Jukkola, R Bloigu, Y Soini, E.-R Savolainen, K Holli, G Blanco, c-erbB-2 positivity is a factor for poor prognosis in breast cancer and poor response to hormonal or chemotherapy treatment in advanced disease. European Journal of Cancer. ,vol. 37, pp. 347- 354 ,(2001) , 10.1016/S0959-8049(00)00395-6