Sample size graphs for "proving the null hypothesis".

作者: William C. Blackwelder , Marie A. Chang

DOI: 10.1016/0197-2456(84)90116-8

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摘要: Abstract Sample size graphs are given for clinical trials designed to test whether an experimental therapy is as effective a standard therapy. We assume dichotomous outcome variable and one-sided of the hypothesis that probability success with greater than by at least some specified amount δ. Graphs significance level α = 0.01, 0.025, 0.05; type II error β 0.10, 0.20; δ 0.20.

参考文章(1)
William C. Blackwelder, “Proving the null hypothesis” in clinical trials Controlled Clinical Trials. ,vol. 3, pp. 345- 353 ,(1981) , 10.1016/0197-2456(82)90024-1