Picosecond laser-induced fluorescence polarization studies of mitoxantrone and tetrakisporphine/DNA complexes

作者: Yizhong Shen , P. Myslinski , Teresa Treszczanowicz , Yixian Liu , J. A. Koningstein

DOI: 10.1021/J100198A052

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摘要: The picosecond time-resolved fluorescence spectra of complexes the drug molecules tetrakis(4-N-methylpyridyl)porphine (H 2 TMPyP) and mitoxantrone (MX) complexed with DNA in phosphate buffer solution are reported. Time-resolved emission permit assignment bands from intercalated MX H TMPyP as well that externally bound to DNA. is facilitated by results both isotropic anisotropic spectroscopies. decay 240±50 ps for 10

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