Irradiation twenty-four hours preoperatively

作者: Alfred S. Ketcham , Robert C. Hoye , Paul B. Chretien , Kirkland C. Brace

DOI: 10.1016/0002-9610(69)90214-1

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摘要: Abstract A clinical study of preoperative irradiation was established as a result experimental studies which indicated that local recurrence and metastases could essentially be eliminated by administering irradiation. Using single 2,000 or 1,500 r dose twenty-four hours before surgery, there high incidence complications. Seventy-nine patients were then studied in carefully controlled double-blind using 1,000 preoperatively. All lesions squamous cell cancers the oral pharyngolaryngeal area excised standard but aggressive surgical procedures. The postoperative complications significantly increased with Although definite trend toward decrease irradiation, no statistically significant rate operative wound, nor any tendency metastases; neither patient survival prolonged. gave results again tumors human subjects do not necessarily behave expected on basis tumor systems.

参考文章(18)
W R Inch, J A Credie, Preoperative use of a single dose of x-rays. pp. 398- ,(1964)
Richard V. Eck, Robert R. Smith, Peter D. Olch, An experimental study of the effect of irradiation on the dissemination of cancer. Cancer Research. ,vol. 19, pp. 464- 467 ,(1959)
Jack C. Fisher, Alfred S. Ketcham, Roxane B. Hume, Richard A. Malmgren, Significance of cancer cells in operative wounds American Journal of Surgery. ,vol. 114, pp. 514- 519 ,(1967) , 10.1016/0002-9610(67)90009-8
W. E. POWERS, J. H. OGURA, Preoperative Irradiation in Head and Neck Cancer Surgery Archives of Otolaryngology-head & Neck Surgery. ,vol. 81, pp. 153- 160 ,(1965) , 10.1001/ARCHOTOL.1965.00750050160010
Marvin S. Arons, Robert R. Smith, Max H. Myers, Significance of cancer cells in operative wounds Cancer. ,vol. 14, pp. 1041- 1044 ,(1961) , 10.1002/1097-0142(196109/10)14:5<1041::AID-CNCR2820140519>3.0.CO;2-V
Malcolm H. McGavran, Joseph H. Ogura, William E. Powers, Small-Dose Preoperative Radiation Therapy Radiology. ,vol. 83, pp. 509- 519 ,(1964) , 10.1148/83.3.509
Bernard H. Feder, Phyllis B. Blair, PREOPERATIVE IRRADIATION: EVALUATION BY A SIMPLE EXPERIMENTAL MODEL. Radiology. ,vol. 83, pp. 111- 119 ,(1964) , 10.1148/83.1.111
Ulrich K. Henschke, Edgar L. Frazell, Basil S. Hilaris, James J. Nickson, H. Randall Tollefsen, Elliot W. Strong, LOCAL RECURRENCES AFTER RADICAL NECK DISSECTION WITH AND WITHOUT PREOPERATIVE X-RAY THERAPY. Radiology. ,vol. 82, pp. 331- 332 ,(1964) , 10.1148/82.2.331