Why the maternal brain

作者: C. H. Kinsley , E. Amory-Meyer

DOI: 10.1111/J.1365-2826.2011.02194.X

关键词:

摘要: In the rat, change from a virgin/nulliparous female to maternal animal takes place at many levels. A subtle developmental wave washes over nervous system and transforms her largely self-centred offspring-directed, personal care protection of genetically-related offspring, indifference ardour. Such is preceded by substantial apparently permanent neural alterations, depth which results in brain, basis present review. The neuroplasticity pregnancy, inherent brain and, we believe, representative full expression system's capacity, result significant hormonal other neurochemical actions. It striking changes that are associated with, necessary for, successful reproduction. We discuss some these their ramifications. Collectively, they represent culmination mammalian evolution have led development social characteristic higher orders mammal, including human. also examine different facets beginning with review genes involved behaviour, subsequent 'expression' brain. next olfaction manner this major sense draws rich sensory milieu mother regulate support behaviour. Last, 'whys' theoretical foray into reasons for such alterations. focus on male's potential role as raison d'etre manifest alterations his mate's end, it clear undergoes reorganisation en route motherhood, deep enduring.

参考文章(85)
G. González-Mariscal, C.H. Kinsley, 3 – From Indifference to Ardor: The Onset, Maintenance, and Meaning of the Maternal Brain Hormones, brain and behavior. ,vol. 3, pp. 109- 138 ,(2009) , 10.1016/B978-008088783-8.00003-6
Thomas R. Insel, Michael Numan, The Neurobiology of Parental Behavior ,(2003)
Craig H. Bailey, Maurizio Giustetto, Yan-You Huang, Robert D. Hawkins, Eric R. Kandel, Is heterosynaptic modulation essential for stabilizing Hebbian plasticity and memory Nature Reviews Neuroscience. ,vol. 1, pp. 11- 20 ,(2000) , 10.1038/35036191
Craig H. Kinsley, Lisa Madonia, Gordon W. Gifford, Kara Tureski, Garrett R. Griffin, Catherine Lowry, Jamison Williams, Jennifer Collins, Heather McLearie, Kelly G. Lambert, Motherhood improves learning and memory Nature. ,vol. 402, pp. 137- 138 ,(1999) , 10.1038/45957
David M. Buss, The Evolution of Desire ,(1994)
Nga Ho, Jason A. Liauw, Frank Blaeser, Feng Wei, Silva Hanissian, Lisa M. Muglia, David F. Wozniak, Anthony Nardi, Kara L. Arvin, David M. Holtzman, David J. Linden, Min Zhuo, Louis J. Muglia, Talal A. Chatila, Impaired Synaptic Plasticity and cAMP Response Element-Binding Protein Activation in Ca2+/Calmodulin-Dependent Protein Kinase Type IV/Gr-Deficient Mice The Journal of Neuroscience. ,vol. 20, pp. 6459- 6472 ,(2000) , 10.1523/JNEUROSCI.20-17-06459.2000
John R. O'Kusky, Ping Ye, A. Joseph D'Ercole, Insulin-Like Growth Factor-I Promotes Neurogenesis and Synaptogenesis in the Hippocampal Dentate Gyrus during Postnatal Development The Journal of Neuroscience. ,vol. 20, pp. 8435- 8442 ,(2000) , 10.1523/JNEUROSCI.20-22-08435.2000
H. M. Bruce, D. M. V. Parrott, Role of Olfactory Sense in Pregnancy Block by Strange Males Science. ,vol. 131, pp. 1526- 1526 ,(1960) , 10.1126/SCIENCE.131.3412.1526
Craig Howard Kinsley, Haddis Tujuba, Elizabeth E. A. Meyer, When Mothers Go Wrong: Likely Neural Undercurrents Related to Poor Parenting Frontiers in Psychiatry. ,vol. 2, pp. 26- 26 ,(2011) , 10.3389/FPSYT.2011.00026