Induction of lysine imbalance in rats: relationships between tissue amino acids and diet.

摘要: We examined the ability of wheat gluten or casein diets supplemented with arginine, indispensable (IAA) branched-chain (BCAA) amino acids (inhibitors lysine transport into brain slices in vitro) to induce changes tissue concentrations consistent occurrence imbalance. Tissue were several-fold higher male, 60--65 g rats Sprague-Dawley strain fed for 1 day a 6% basal diet than diets. Feeding containing 5% mixture all IAA except changed and other resemble those from Growth depressions caused by arginine consistently associated large decreases increases ornithine concentrations. supplements BCAA frequently accompanied small insignificant content, content these acids. Plasma generally decreased less brain. The arginine-induced decrease concentration is hypothesis that induction acid imbalances may involve competition an indispensable, limiting acid; growth appear factors as well.