Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen.

作者: S.S. Molloy , P.A. Bresnahan , S.H. Leppla , K.R. Klimpel , G Thomas

DOI: 10.1016/S0021-9258(18)42016-9

关键词:

摘要: … Leu-Arg-Arg-MCA prompted the use of Arg-Val-Arg-Arg as the peptide substrate boc-Leu-Lys-Arg… boc-Gly-Lys-Arg-MCA 1.5 pH and Calcium Dependence-Several buffers shown preboc-…

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