Recent Advances in Chemoenzymatic Bioconjugation Methods

作者: Jesse M. McFarland and David Rabuka

DOI: 10.4137/OCI.S17957

关键词:

摘要: Genetic fusions of either full enzymes or peptide tags with a protein interest have enabled the synthesis conjugates precise control over site attachment and number payloads incorporated. Engineering glycans, depending on application, can lead to similar for nonengineered glycoproteins. Recent advances in field chemoenzymatic modifications proteins site-specific conjugation will be reviewed. These techniques been used an array fields execution innovative valuable experiments. Specific industrial applications these technologies highlighted.

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