Role of Metal Ions in Antisense and Antigene Strategies

作者: Bernhard Lippert , Marc Leng

DOI: 10.1007/978-3-662-03815-4_5

关键词:

摘要: The fields of gene regulation by antisense and antigene agents the therapeutic use oligonucleotides in general are developing at a rapid pace. present status this research various approaches briefly reviewed. Specific attention is given to role metal ions these processes particular potential usefulness platinum am(m)ine complexes as site-directed oligonucleotide cross-linking agents.

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