Chronic infection and inflammation: Hallmarks of diabetic foot ulcers
作者： Suman Santra , Atul Rawat , Dhamotharan Pattarayan , Sashwati Roy
DOI: 10.1016/B978-0-12-816413-6.00003-4
关键词:
摘要: Abstract The pathogenesis of the diabetic foot ulcer (DFU) is very complex. Among other known factors, such as poor innervation and vascularization, chronic infection inflammation are critical factors that result in chronicity these wounds. Novel emerging concepts inflammatory response discussed this chapter. Lack adequate solutions for treatment wound infections antibiotic resistant biofilm may serious consequences, including quality life amputations patients with diabetes. can counter threats urgently needed. A thorough understanding principles immune dysfunction insufficient resolution will lead to innovative interventions drive a towards inflammation, which conducive healing.
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