Wolbachia in Aedes mosquitoes: towards biological control of vector-borne diseases

摘要: Dengue causes an enormous impact on global public health with 50 million cases every year. Vector control is predominantly focused the application of insecticides against adult mosquitoes. However, current methods vector are often not sustainable for long periods because emergence insecticide resistance. In this context, discovery and alternative extremely important. A new approach biological diseases transmitted by mosquitoes has recently been proposed that uses endosymbiotic bacterium ( Wolbachia pipientis) in order to interfere transmission pathogens. The advantage using infected females have a reproductive due cytoplasmic incompatibility (CI), which leads increase numbers individuals wild. When Aedes aegypti (that naturally lack bacterium) were transinfected it was discovered presence bacteria inhibits replication pathogens such as dengue chikungunya viruses well filarial avian malaria parasites. More Ae. harbouring Drosophila-Wolbachia strain released Australia able quickly spread chapter we review possibility applying potential human mosquito vectors.