Metabolic profiling with gas chromatography-mass spectrometry and its application to clinical medicine.
作者： Toshimitsu Niwa
DOI: 10.1016/S0378-4347(00)80688-X
关键词:
摘要: Nowadays, metabolic profiling is widely applied in clinical medicine for the diagnosis and study of human diseases. The number these applications their diversity have increased rapidly past few years. This review summarizes recent advances methods sample pretreatment application GC-MS to uraemia, diabetes mellitus, dicarboxylic aciduria other organic acidurias. High-resolution well suited profile analysis disorders.
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sci-hub.se 参考文章(236)
A. Russell, B. Levin, V.G. Oberholzer, L. Sinclair, Hyperammonaemia. A new instance of an inborn enzymatic defect of the biosynthesis of urea. The Lancet. ,vol. 280, pp. 699- 700 ,(1962) , 10.1016/S0140-6736(62)90508-1
B McArthur, A P Sarnaik, Quantification of short-chain fatty acids in plasma. Clinical Chemistry. ,vol. 28, pp. 1983- 1984 ,(1982) , 10.1093/CLINCHEM/28.9.1983
G Spiteller, P Pfeifer, M Ende, [Contamination by use of Extrelut columns (author's transl)]. Journal of Chromatography A. ,vol. 183, pp. 1- 7 ,(1980)
Goodman Si, An introduction to gas chromatography-mass spectrometry and the inherited organic acidemias. American Journal of Human Genetics. ,vol. 32, pp. 781- 792 ,(1980)
Hartmut M. Liebich, Claudia Först, N-Methylation and N,N-dimethylation of amino acids: An artifact production in the analysis of organic acids using diazomethane as derivatizing agent Journal of Chromatography A. ,vol. 338, pp. 33- 40 ,(1985) , 10.1016/0378-4347(85)80067-0
Toshimitsu Niwa, Kenji Maeda, Hiroaki Asada, Masao Shibata, Toyokazu Ohki, Akira Saito, Hiroshi Furukawa, Gas chromatographic—mass spectrometric analysis of organic acids in renal tissue biopsy Journal of Chromatography B: Biomedical Sciences and Applications. ,vol. 230, pp. 1- 6 ,(1982) , 10.1016/S0378-4347(00)81424-3
U. Langenbeck, A. Mench-Hoinowski, K.-P. Dieckmann, H.-U. Möhring, M. Petersen, O-trimethylsilylquinoxalinol derivatives of aromatic α-keto acids Journal of Chromatography B: Biomedical Sciences and Applications. ,vol. 145, pp. 185- 193 ,(1978) , 10.1016/S0378-4347(00)81338-9
Toshiyuki Ando, Karsten Rasmussen, John M. Wright, William L. Nyhan, Isolation and identification of methylcitrate, a major metabolic product of propionate in patients with propionic acidemia. Journal of Biological Chemistry. ,vol. 247, pp. 2200- 2204 ,(1972) , 10.1016/S0021-9258(19)45512-9
Toshmitsu Niwa, Naoya Yamamoto, Kenji Maeda, Kazumasa Yamada, Toyokazu Ohki, Masami Mori, Gas chromatographic--mass spectrometric analysis of polyols in urine and serum of uremic patients. Identification of new deoxyalditols and inositol isomers. Journal of Chromatography B: Biomedical Sciences and Applications. ,vol. 277, pp. 25- 39 ,(1983) , 10.1016/S0378-4347(00)84820-3
Albert Zlatkis, Fikry Andrawes, A micro method for the determination of volatile metabolites in biological samples. A preliminary report. Journal of Chromatography A. ,vol. 112, pp. 533- 538 ,(1975) , 10.1016/S0021-9673(00)99982-5