Control of Antimicrobial Resistance Requires an Ethical Approach.

作者: Ben Parsonage , Philip K. Hagglund , Lloyd Keogh , Nick Wheelhouse , Richard E. Brown

DOI: 10.3389/FMICB.2017.02124

关键词:

摘要: Ethical behavior encompasses actions that benefit both self and society. This means tackling antimicrobial resistance (AMR) becomes an ethical obligation, because the prospect of declining anti-infectives affects everyone. Without preventive action, loss drugs have saved lives over past century, will condemn ourselves, people we know, don't to unacceptable risk untreatable infection. Policies aimed at extending life should be considered within framework, in order balance choice, range, quality against stewardship activities. Conserving availability effectiveness for future use not compromise today's patients. Practices such as prophylaxis healthy 'at risk' receive full debate. There are additional considerations AMR involving veterinary care, agriculture, relevant bio-industries. Restrictions farmers potentially threaten quantity food production with economic consequences. Antibiotics companion animals do necessarily spare those used humans. While low-income countries cannot afford much-needed drugs, pharmaceutical companies reluctant develop novel agents short-term return only. Public demand encourages over-the-counter, internet, black market, counterfeit all which international control. Prescribers themselves require educational support therapeutic choice collateral damage body environment. Predicted mortality due provides justification co-operation, commitment investment surveillance along development drugs. arguments for, against, control strategies presented discussed this review.

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