Dystonic reaction associated with ondansetron administration in a patient with normal pressure hydrocephalus

摘要: A 77-year-old female with normal pressure hydrocephalus underwent urgent revision of the abdominal component a ventriculoperitoneal shunt. Upon emergence from an uneventful general anesthetic, patient exhibited cogwheel rigidity decerebrate posturing and markedly irregular respiratory rate. This prohibited extubation prompted unplanned intensive care unit admission. Ondansetron was only medication administered that had previously been associated dystonic reactions. In previous procedure, given ondansetron without similar reaction. presentation may have provoked by existing pathology such as her underlying small increases in intracranial pressure.