Calcium signaling in physiology and pathophysiology.
作者： He-ping CHENG , Sheng WEI , Li-ping WEI , Alexei VERKHRATSKY
DOI: 10.1111/J.1745-7254.2006.00399.X
关键词:
摘要: Calcium ions are the most ubiquitous and pluripotent cellular signaling molecules that control a wide variety of processes. The calcium system is represented by relatively limited number highly conserved transporters channels, which execute Ca2+ movements across biological membranes many thousands Ca2+-sensitive effectors. Molecular cascades, responsible for generation signals, tightly controlled themselves genetic factors, tune expression different Ca2+-handling according to adaptational requirements. determine normal physiological reactions development pathological
nature.com
chinaphar.com
core.ac.uk 参考文章(66)
Marcel Leist, Pierluigi Nicotera, Apoptosis Versus Necrosis: The Shape of Neuronal Cell Death Results and Problems in Cell Differentiation. ,vol. 24, pp. 105- 135 ,(1998) , 10.1007/978-3-540-69185-3_6
Michael J. Berridge, Martin D. Bootman, H. Llewelyn Roderick, Calcium signalling: dynamics, homeostasis and remodelling. Nature Reviews Molecular Cell Biology. ,vol. 4, pp. 517- 529 ,(2003) , 10.1038/NRM1155
M. T. Nelson, H. Cheng, M. Rubart, L. F. Santana, A. D. Bonev, H. J. Knot, W. J. Lederer, Relaxation of arterial smooth muscle by calcium sparks Science. ,vol. 270, pp. 633- 637 ,(1995) , 10.1126/SCIENCE.270.5236.633
Peter Vangheluwe, Luc Raeymaekers, Leonard Dode, Frank Wuytack, Modulating sarco(endo)plasmic reticulum Ca2+ ATPase 2 (SERCA2) activity: cell biological implications. Cell Calcium. ,vol. 38, pp. 291- 302 ,(2005) , 10.1016/J.CECA.2005.06.033
George C. Wellman, David J. Nathan, Christine M. Saundry, Guillermo Perez, Adrian D. Bonev, Paul L. Penar, Bruce I. Tranmer, Mark T. Nelson, Ca2+ Sparks and Their Function in Human Cerebral Arteries Stroke. ,vol. 33, pp. 802- 808 ,(2002) , 10.1161/HS0302.104089
Emil C Toescu, Hypoxia sensing and pathways of cytosolic Ca2+ increases. Cell Calcium. ,vol. 36, pp. 187- 199 ,(2004) , 10.1016/J.CECA.2004.02.019
D D Friel, R W Tsien, A caffeine- and ryanodine-sensitive Ca2+ store in bullfrog sympathetic neurones modulates effects of Ca2+ entry on [Ca2+]i. The Journal of Physiology. ,vol. 450, pp. 217- 246 ,(1992) , 10.1113/JPHYSIOL.1992.SP019125
Hideo Mogami, Alexei V Tepikin, Ole H Petersen, Termination of cytosolic Ca2+ signals: Ca2+ reuptake into intracellular stores is regulated by the free Ca2+ concentration in the store lumen. The EMBO Journal. ,vol. 17, pp. 435- 442 ,(1998) , 10.1093/EMBOJ/17.2.435
F. W. Tse, A. Tse, B. Hille, Cyclic Ca2+ changes in intracellular stores of gonadotropes during gonadotropin-releasing hormone-stimulated Ca2+ oscillations. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 9750- 9754 ,(1994) , 10.1073/PNAS.91.21.9750
David G. Nicholls, Mitochondria and calcium signaling. Cell Calcium. ,vol. 38, pp. 311- 317 ,(2005) , 10.1016/J.CECA.2005.06.011