Molecular epidemiology of influenza, RSV, and other respiratory infections among children in Qatar: A six years report (2012-2017).

作者: Hamad E. Al-Romaihi , Maria K. Smatti , Hebah A. Al-Khatib , Peter V. Coyle , Nandakumar Ganesan

DOI: 10.1016/J.IJID.2020.04.008

关键词:

摘要: Abstract Background Studies on the etiology of respiratory infections among children in Qatar and surrounding countries are limited. Objectives To describe prevalence seasonality RSV, influenza, other pathogens Qatar. Methods We retrospectively collected analyzed data 33,404 ( Results At least one pathogen was detected 26,138 (78%) patients. Together, human rhinoviruses (HRV), syncytial virus (RSV), influenza viruses comprised nearly two-thirds all cases, affecting 24%, 19.7%, 18.5%, respectively. A 5-10% recorded for adenovirus, parainfluenza (PIVs), bocavirus (HboV), coronaviruses (HCoVs). Human metapneumovirus (HMPV), enteroviruses, M. pneumonia, parechovirus had prevalences below 5%. While HMPV exhibited strong seasonal activity winter, HRV active during low RSV circulation. The burden exceeds that young age groups, whereas correlated positively with age. Further, HRV, infection rates varied significantly between male females. Conclusion This comprehensive multi-year study provides insights into ILI Qatar, which represents Gulf region. Our results reinforce significance surveillance to improve prevention control strategies, particularly children.

参考文章(53)
Alleyne G, Jamison Dt, Claeson M, Musgrove P, Measham Ar, Evans Db, Mills A, Jha P, Breman Jg, Acute Respiratory Infections in Children -- Disease Control Priorities in Developing Countries World Bank. ,(2006)
Karolina Bednarska, E. Hallmann-Szelińska, K. Kondratiuk, L. B. Brydak, Evaluation of the Activity of Influenza and Influenza-Like Viruses in the Epidemic Season 2013/2014. Advances in Experimental Medicine and Biology. ,vol. 857, pp. 1- 7 ,(2015) , 10.1007/5584_2015_116
Lan Fang Tang, Hong Feng Tang, Tian Lin Wang, Zhi Min Chen, Viral pathogens of acute lower respiratory tract infection in China. Indian Pediatrics. ,vol. 45, pp. 971- 975 ,(2008)
L. Ren, R. Gonzalez, Z. Wang, Z. Xiang, Y. Wang, H. Zhou, J. Li, Y. Xiao, Q. Yang, J. Zhang, L. Chen, W. Wang, Y. Li, T. Li, X. Meng, Y. Zhang, G. Vernet, G. Paranhos-Baccalà, J. Chen, Q. Jin, J. Wang, Prevalence of human respiratory viruses in adults with acute respiratory tract infections in Beijing, 2005-2007. Clinical Microbiology and Infection. ,vol. 15, pp. 1146- 1153 ,(2009) , 10.1111/J.1469-0691.2009.02746.X
Edward Goldstein, Sharon K. Greene, Donald R. Olson, William P. Hanage, Marc Lipsitch, Estimating the hospitalization burden associated with influenza and respiratory syncytial virus in New York City, 2003–2011 Influenza and Other Respiratory Viruses. ,vol. 9, pp. 225- 233 ,(2015) , 10.1111/IRV.12325
Leonard R. Krilov, Respiratory Syncytial Virus: Update on Infection, Treatment, and Prevention. Current Infectious Disease Reports. ,vol. 3, pp. 242- 246 ,(2001) , 10.1007/S11908-001-0026-3
Arnold S Monto, Epidemiology of viral respiratory infections The American Journal of Medicine. ,vol. 112, pp. 4- 12 ,(2002) , 10.1016/S0002-9343(01)01058-0
Hirono Otomaru, Taro Kamigaki, Raita Tamaki, Jamie Opinion, Arlene Santo, Edgard Daya, Michiko Okamoto, Mariko Saito, Veronica Tallo, Soccoro Lupisan, Akira Suzuki, Hitoshi Oshitani, Influenza and Other Respiratory Viruses Detected by Influenza-Like Illness Surveillance in Leyte Island, the Philippines, 2010–2013 PLOS ONE. ,vol. 10, ,(2015) , 10.1371/JOURNAL.PONE.0123755
Guillermo Comach, Nimfa Teneza-Mora, Tadeusz J Kochel, Carlos Espino, Gloria Sierra, Daria E Camacho, V Alberto Laguna-Torres, Josefina Garcia, Gloria Chauca, Maria E Gamero, Merly Sovero, Slave Bordones, Iris Villalobos, Angel Melchor, Eric S Halsey, None, Sentinel surveillance of influenza-like illness in two hospitals in Maracay, Venezuela: 2006-2010. PLOS ONE. ,vol. 7, ,(2012) , 10.1371/JOURNAL.PONE.0044511
Mohamed Ghaith Alkuwari, Nagah A Aziz, Zaher AS Nazzal, Saad A Al-Nuaimi, None, Pandemic influenza A/H1N1 vaccination uptake among health care workers in Qatar: motivators and barriers. Vaccine. ,vol. 29, pp. 2206- 2211 ,(2011) , 10.1016/J.VACCINE.2010.08.093