The Expressions and Mechanisms of Sarcomeric Proteins in Cancers.

作者: Xiaojing Yang , Hanru Ren , Xiaomao Guo , Chaosu Hu , Jie Fu

DOI: 10.1155/2020/8885286

关键词:

摘要: The sarcomeric proteins control the movement of cells in diverse species, whereas deregulation can induce tumours model organisms and occurs human carcinomas. Sarcomeric are recognized as oncogene related to tumor cell metastasis. Recent insights into their expressions functions have led new cancer therapeutic opportunities. In this review, we appraise evidence for genes discuss cancer-relevant biological functions, potential mechanisms by which activity is altered cancer.

参考文章(166)
Nobutaka Edakuni, Kenji Ikuta, Seiji Yano, Emiko Nakataki, Hiroaki Muguruma, Hisanori Uehara, Masachika Tani, Jun Yokota, Hisamichi Aizawa, Saburo Sone, Restored Expression of the MYO18B Gene Suppresses Orthotopic Growth and the Production of Bloody Pleural Effusion by Human Malignant Pleural Mesothelioma Cells in SCID Mice Oncology Research. ,vol. 16, pp. 235- 243 ,(2006) , 10.3727/000000006783981062
Jessica L. Ouderkirk, Mira Krendel, Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis. Cytoskeleton. ,vol. 71, pp. 447- 463 ,(2014) , 10.1002/CM.21187
Samantha J. King, Karolin Nowak, Narendra Suryavanshi, Ian Holt, Catherine M. Shanahan, Anne J. Ridley, Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration Cytoskeleton. ,vol. 71, pp. 423- 434 ,(2014) , 10.1002/CM.21182
C M Fife, J A McCarroll, M Kavallaris, Movers and shakers: cell cytoskeleton in cancer metastasis British Journal of Pharmacology. ,vol. 171, pp. 5507- 5523 ,(2014) , 10.1111/BPH.12704
Vera Dugina, Natalya Khromova, Vera Rybko, Oleg Blizniukov, Galina Shagieva, Christine Chaponnier, Boris Kopnin, Pavel Kopnin, Tumor promotion by γ and suppression by β non-muscle actin isoforms Oncotarget. ,vol. 6, pp. 14556- 14571 ,(2015) , 10.18632/ONCOTARGET.3989
Kenji Hibi, Hiroshi Nemoto, Kazuyoshi Ishibashi, Makiko Sakata, Atsushi Shirahata, Mitsuo Saito, Kazuma Sakuraba, Gaku Kigawa, Tetsuhiro Goto, Yutaka Sanada, Hiroki Mizukami, Vimentin methylation as a marker for advanced colorectal carcinoma. Anticancer Research. ,vol. 29, pp. 279- 281 ,(2009)
Yingjia Sun, Xinghao Ai, Shengping Shen, Shun Lu, NF-κB-mediated miR-124 suppresses metastasis of non-small-cell lung cancer by targeting MYO10 Oncotarget. ,vol. 6, pp. 8244- 8254 ,(2015) , 10.18632/ONCOTARGET.3135
Jinhua Xu, Yinghua Chen, Dezheng Huo, Andrey Khramtsov, Galina Khramtsova, Chunling Zhang, Kathleen H. Goss, Olufunmilayo I. Olopade, β-catenin regulates c-Myc and CDKN1A expression in breast cancer cells. Molecular Carcinogenesis. ,vol. 55, pp. 431- 439 ,(2016) , 10.1002/MC.22292
Ruirui Kong, Fengshuang Yi, Pushuai Wen, Jianghong Liu, Xiaoping Chen, Jinqi Ren, Xiaofei Li, Yulong Shang, Yongzhan Nie, Kaichun Wu, Daiming Fan, Li Zhu, Wei Feng, Jane Y. Wu, Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression Journal of Clinical Investigation. ,vol. 125, pp. 4407- 4420 ,(2015) , 10.1172/JCI81673
Sanja Ivkovic, Christopher Beadle, Sonal Noticewala, Susan C Massey, Kristin R Swanson, Laura N Toro, Anne R Bresnick, Peter Canoll, Steven S Rosenfeld, None, Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens. Molecular Biology of the Cell. ,vol. 23, pp. 533- 542 ,(2012) , 10.1091/MBC.E11-01-0039