作者: Charlène Bouyer , Pu Chen , Sinan Güven , Tuğrul Tolga Demirtaş , Thomas J. F. Nieland
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摘要: A bio-acoustic levitational assembly method for engineering of multilayered, 3D brainlike constructs is presented. Acoustic radiation forces are used to levitate neuroprogenitors derived from human embryonic stem cells in multilayered fibrin tissue constructs. The neuro-progenitor subsequently differentiated neural cells, resulting a neuronal construct with inter and intralayer neurite elongations.