Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis.
作者： Daniele Castagnolo , Marco Radi , Filippo Dessì , Fabrizio Manetti , Manuela Saddi
DOI: 10.1016/J.BMCL.2009.02.101
关键词:
摘要: A series of novel enantiomerically pure azole derivatives was synthesized. The new compounds, bearing both an imidazole as well a triazole moiety, were evaluated antimycobacterial agents. One them proved to have activity against Mycobaterium tuberculosis comparable those the classical antibacterial/antifungal drugs Econazole and Clotrimazole.
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