Non-heart-beating donors: One response to the organ shortage

摘要: Summary The use of organs from NHBDs is beginning to gain acceptance as a method help alleviate the current organ shortage. This shown by number OPOs that now have protocols for retrieving NHBDs. In controlled setting, can be expected yield kidneys and, in preliminary studies, extrarenal function similarly those retrieved HBDs. best renal preservation after retrieval appears machine perfusion—as result which, rates delayed graft reduced significantly. Experimental work may further limit damaging effects warm ischemia. Although could significant impact on transplantation, transplantation will much smaller. For this reason, absence HBDs, uncontrolled most decreasing disparity between donors and potential recipients. However, involving are logistically more complex must ischemia while, at same time, satisfying issues consent any procedure performed preparation donation. Because large healthcare professionals involved with NHBDs, discussions them on-site ethics committees extremely important. has historical precedent, many unaware concept not new. Therefore, education these essential. Likewise, transplant institution way medical boards or IRBs should approve involve Active regarding allay fears impropriety maintain public trust. If our approach scientifically sound, ethically based, expertly applied, major Despite resurgence interest we lose sight fact do realize full