Acute Leukemia Characteristics are Different Around the World: the Mexican Perspective

作者: David Gómez-Almaguer , Edson René Marcos-Ramírez , Efreen Horacio Montaño-Figueroa , Guillermo J Ruiz-Argüelles , Carlos Roberto Best-Aguilera

DOI: 10.1016/J.CLML.2016.09.003

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摘要: Abstract Background The incidence of acute leukemia (AL) has increased. Its prognosis is variable and depends on several baseline characteristics with a highly heterogeneous presentation. In Mexico, large-scale descriptive studies have not yet been published; the objective this study was to analyze initial basic patients diagnosed AL in our population. Patients Methods multicenter, retrospective study, 1018 patients ≥ 16 years age between 2009 2014, were included. We described age, gender, complete blood count, subtype according flow cytometry analysis. Results Acute lymphoblastic (ALL) as common myeloid (AML) (51% vs. 49%). median 31 years. Only 9.6% ALL positive for Philadelphia chromosome. No gender differences observed. at presentation AML 43 promyelocytic most frequent (38.3%), 37 Conclusion equally patients ≥16 age. Philadelphia-positive prevalence less than that reported literature. cases occur younger comparison other countries. There higher rate among compared non-Latin American populations. This largest ever performed Mexico regarding data.

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