摘要: We have been witnessing an increased interest in bacteriophage studies focused on their use as antibacterial agents to fight pathogenic bacteria. This is a consequence of the phages' ability lyse bacterial host. Until recently, little was known about mechanisms used by mycobacteriophages induce lysis complex hosts. However, Ms6-induced changed this scenario and provided new insights into bacteriophage-induced lysis. Specific protein genes identified mycobacteriophage genomes, reflecting particular mycobacterial cell envelope composition. These include enzymes that target mycolic acid-containing lipids proteins participate secretion phage endolysin, functioning chaperone-like proteins. chapter focuses current knowledge mycobacteriophage-induced lysis, starting with overview basic features players.
asmscience.org参考文章(68)
Daniel C. Nelson, Mathias Schmelcher, Lorena Rodriguez-Rubio, Jochen Klumpp, David G. Pritchard, Shengli Dong, David M. Donovan, Endolysins as antimicrobials. Advances in Virus Research. ,vol. 83, pp. 299- 365 ,(2012) , 10.1016/B978-0-12-394438-2.00007-4
Ana Filipa Morais Esteves Gil, Functional analysis of lysB gene from the lysis module of mycobacteriophage Ms6 ,(2011)
Maria João Catalão, Filipa Gil, José Moniz-Pereira, Madalena Pimentel, The mycobacteriophage Ms6 encodes a chaperone-like protein involved in the endolysin delivery to the peptidoglycan. Molecular Microbiology. ,vol. 77, pp. 672- 686 ,(2010) , 10.1111/J.1365-2958.2010.07239.X
Erlan Ramanculov, Ry Young, An ancient player unmasked: T4 rI encodes a t-specific antiholin. Molecular Microbiology. ,vol. 41, pp. 575- 583 ,(2001) , 10.1046/J.1365-2958.2001.02491.X
Jean Tweedy Walker, Donald H. Walker, Mutations in Coliphage P1 Affecting Host Cell Lysis Journal of Virology. ,vol. 35, pp. 519- 530 ,(1980) , 10.1128/JVI.35.2.519-530.1980
Joel Berry, Christos Savva, Andreas Holzenburg, Ry Young, The lambda spanin components Rz and Rz1 undergo tertiary and quaternary rearrangements upon complex formation Protein Science. ,vol. 19, pp. 1967- 1977 ,(2010) , 10.1002/PRO.485
R Ziermann, B Bartlett, R Calendar, G E Christie, Functions involved in bacteriophage P2-induced host cell lysis and identification of a new tail gene. Journal of Bacteriology. ,vol. 176, pp. 4974- 4984 ,(1994) , 10.1128/JB.176.16.4974-4984.1994
Jan Borysowski, Beata Weber-Dąbrowska, Andrzej Górski, Bacteriophage Endolysins as a Novel Class of Antibacterial Agents Experimental Biology and Medicine. ,vol. 231, pp. 366- 377 ,(2006) , 10.1177/153537020623100402
Mart Krupovič, Virginija Cvirkaitė-Krupovič, Dennis H. Bamford, Identification and functional analysis of the Rz/Rz1-like accessory lysis genes in the membrane-containing bacteriophage PRD1. Molecular Microbiology. ,vol. 68, pp. 492- 503 ,(2008) , 10.1111/J.1365-2958.2008.06165.X
Ting Pang, Taehyun Park, Ry Young, Mutational analysis of the S21pinholin Molecular Microbiology. ,vol. 76, pp. 68- 77 ,(2010) , 10.1111/J.1365-2958.2010.07080.X