Unraveling the soul of autoimmune diseases: pathogenesis, diagnosis and treatment adding dowels to the puzzle.

摘要: The pathogenesis of autoimmune diseases (ADs) is characterized by a complex interaction between genetic, immune defects, environmental and hormonal factors. concept "mosaic autoimmunity" deals with the multi-factorial origin diversity expression ADs in humans. Genetic leads to predisposition developing an syndrome, but presence external or endogenous factor, recently called "exposome," essential triggering response. Infections as well expositions different other agents have been identified potential trigger for ADs. A new namely autoimmune/inflammatory syndrome induced adjuvants, has defined alluding key role adjuvant inducing immune-mediated condition. Aluminum silicone, respectively found vaccines breast implants, are most commonly known adjuvants charged development conditions. Similarly playing chess, unraveling every discovery adding move game aiming at checkmating