Switch to second-line ART in West African routine care: incidence and reasons for switching

摘要: In sub-Saharan Africa, while antiretroviral therapy (ART) becomes widely available, access to biological measurements monitor patients under ART remains scarce, making the management of difficult. We described switching second-line where HIV care is provided mainly in secondary health-care structures, region Segou, Mali. Of 865 patients, followed for a median time 15 months, 40 switched (3.3 switches/100 person years). Reason was failure 18 (after 21 months median) and severe intolerance 13 three median). Switching occurred earlier when motivated by than failure. The low rate switch compares well with other studies, but compared expected failure, may indicate that physicians are reluctant treatment options limited.