Insights from three-dimensional echocardiographic laser stereolithography. Effect of leaflet funnel geometry on the coefficient of orifice contraction, pressure loss, and the Gorlin formula in mitral stenosis.

摘要: Background Three-dimensional echocardiography can allow us to address uniquely three-dimensional scientific questions, for example, the hypothesis that impact of a stenotic valve depends not only on its limiting orifice area but also geometry proximal orifice. This affect coefficient contraction (Cc=effective/anatomic area), which is important because given flow rate and anatomic area, lower Cc gives higher velocity pressure gradient, Cc, routinely assumed constant in Gorlin equation, may vary with shape (60% flat plate, 100% tube). To date, it has been possible study this actual shapes patients. Methods Results reconstructed geometries typical spectrum patients mitral stenosis: mobile doming, intermediate conical, relatively immobile valves. Each was constructed areas 0.5, 1.0, 1.5 cm2 by stere...