Revisiting immunosurveillance and immunostimulation: Implications for cancer immunotherapy.

摘要: Experimental and clinical experience demonstrates that the resolution of a pathogenic challenge depends not only on presence or absence an immune reaction, but also initiation proper type reaction. The non-protective reaction will result in lack protection, may exacerbate underlying condition. For example, cancer, constituents system have been shown to augment tumor proliferation, angiogenesis, metastases. This review discusses duality role from theories immunosurveillance immunostimulation current studies, which illustrate has both protective tumor-promoting neoplasia. potential using chemotherapy inhibit is discussed.