Negative affect in offspring of depressed mothers is predicted by infant cortisol levels at 6 months and maternal depression during pregnancy, but not postpartum.

摘要: This study tests the hypothesis that maternal depression during pregnancy predicts temperament in offspring aged 6 m to 5 y. Previous studies have shown is related negative affect and certain factors, such as behavioral inhibition, children predict affective disorders. Here, divided into vs. postpartum. Maternal was determined by Beck Depression Inventory (BDI) throughout postpartum (prospectively) a diagnostic interview (SCID) at months The data show pregnancy, but not postpartum, predicted ratings of offspring. Importantly, symptoms mother were used control variable analyses order for potential bias mother's mood. In addition, cortisol levels response mild stressor age infants toddlers. We conclude effects on problems vulnerability mental illness may be mediated altered enhanced stress responsiveness.